DataSet Record GDS3643: Expression Profiles Data Analysis Tools Sample Subsets
Title: D-serine effect on the brain: dose response
Cluster AnalysisGDS3643 Cluster Image
Summary: Analysis of forebrains of animals treated with up to 500 mg/kg D-serine for 96 hours. D-serine is involved in many physiological processes through its interaction with the glycine binding site of the NMDA receptor. Results provide insight into the impact of D-serine exposure on neuronal functions.
Organism: Rattus norvegicus
Platform: GPL1355: [Rat230_2] Affymetrix Rat Genome 230 2.0 Array
  • Davidson ME, Kerepesi LA, Soto A, Chan VT. D-Serine exposure resulted in gene expression changes implicated in neurodegenerative disorders and neuronal dysfunction in male Fischer 344 rats. Arch Toxicol 2009 Aug;83(8):747-62. PMID: 19212759
Reference Series: GSE10748 Sample count: 24
Value type: count Series published: 2008/03/08