Analysis of various mononuclear cells from patients with severe triple-vessel coronary artery disease (CAD). CD34+ stem cells, CD4+ T-helper cells, CD14+ resting monocytes, LPS-stimulated monocytes, and macrophages were examined. Results provide insight into the pathophysiology of atherosclerosis.
Schirmer SH, Fledderus JO, van der Laan AM, van der Pouw-Kraan TC et al. Suppression of inflammatory signaling in monocytes from patients with coronary artery disease. J Mol Cell Cardiol 2009 Feb;46(2):177-85. PMID: 19059264
van der Pouw Kraan TC, Schirmer SH, Fledderus JO, Moerland PD et al. Expression of a retinoic acid signature in circulating CD34 cells from coronary artery disease patients. BMC Genomics 2010 Jun 21;11:388. PMID: 20565948
