DataSet Record GDS3717: Expression Profiles Data Analysis Tools Sample Subsets
Title: NOTCH antagonist SAHM1 effect on T-ALL cell lines
Cluster AnalysisGDS3717 Cluster Image
Summary: Analysis of HPB-ALL and KOPT-K1 cells treated with SAHM1, an antagonist of the NOTCH transcription factor. SAHM1 is an alpha-helical hydrocarbon stapled peptide derived from MAML1. Results provide insight into the specificity of the antagonistic effect of SAHM1 on gene expression driven by NOTCH.
Organism: Homo sapiens
Platform: GPL570: [HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array
  • Moellering RE, Cornejo M, Davis TN, Del Bianco C et al. Direct inhibition of the NOTCH transcription factor complex. Nature 2009 Nov 12;462(7270):182-8. PMID: 19907488
Reference Series: GSE18198 Sample count: 12
Value type: transformed count Series published: 2009/11/12