DataSet Record GDS3724: Expression Profiles Data Analysis Tools Sample Subsets
Title: Effects of high-fat maternal diet and transcription factor Cited2 deficiency on embryos
Cluster AnalysisGDS3724 Cluster Image
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Summary: Analysis of Cited2-deficient, C57BL6/J embryos from high-fat diet mothers. Maternal high-fat diet results in abnormal laterality and cleft palate in Cited2 -/- embryos. Results provide insight into a gene-environment interaction with significant consequences for patterning the developing embryo.
Organism: Mus musculus
Platform: GPL6887: Illumina MouseWG-6 v2.0 expression beadchip
Citation:
  • Bentham J, Michell AC, Lockstone H, Andrew D et al. Maternal high-fat diet interacts with embryonic Cited2 genotype to reduce Pitx2c expression and enhance penetrance of left-right patterning defects. Hum Mol Genet 2010 Sep 1;19(17):3394-401. PMID: 20566713
Reference Series: GSE22558 Sample count: 12
Value type: transformed count Series published: 2010/06/24