Snord116del mutant hypothalamus response to neonatal starvation
Summary:
Analysis of P5 and P13 hypothalami from Snord116del animals, a model for Prader-Willi syndrome, a disease that involves infantile feeding difficulties and failure to thrive. P5 neonates subjected to 6h starvation. Results provide insight into the role of Snord116 in feeding regulation in neonates.
Ding F, Li HH, Li J, Myers RM et al. Neonatal maternal deprivation response and developmental changes in gene expression revealed by hypothalamic gene expression profiling in mice. PLoS One 2010 Feb 24;5(2):e9402. PMID: 20195375
