DataSet Record GDS3799: Expression Profiles Data Analysis Tools Sample Subsets
Title: Bone morphogenetic protein type II receptor mutation effect on lung
Cluster AnalysisGDS3799 Cluster Image
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Summary: Analysis of lung from transgenics expressing a BMPR2 tail domain mutation (BMPR2R899X) in smooth muscle. Nine weeks of BMPR2R899X expression can result in elevated right ventricular systolic pressures (RVSP), producing a mutant phenotype relevant to human pulmonary arterial hypertension (PAH).
Organism: Mus musculus
Platform: GPL1261: [Mouse430_2] Affymetrix Mouse Genome 430 2.0 Array
Citation:
  • West J, Harral J, Lane K, Deng Y et al. Mice expressing BMPR2R899X transgene in smooth muscle develop pulmonary vascular lesions. Am J Physiol Lung Cell Mol Physiol 2008 Nov;295(5):L744-55. PMID: 18723761
Reference Series: GSE11018 Sample count: 6
Value type: count Series published: 2008/06/01