Cold effect on inguinal white adipose tissue: time course
Summary:
Analysis of white adipose tissue (WAT) from C57/Bl6 males exposed to 4 degrees C for up to 5 weeks. The cold induces an angiogenic switch, and conversion to a more BAT-like phenotype, in WAT. Results provide insight into molecular mechanisms of angiogenesis in relation to adipose tissue metabolism.
Xue Y, Petrovic N, Cao R, Larsson O et al. Hypoxia-independent angiogenesis in adipose tissues during cold acclimation. Cell Metab 2009 Jan 7;9(1):99-109. PMID: 19117550
Dong M, Yang X, Lim S, Cao Z et al. Cold exposure promotes atherosclerotic plaque growth and instability via UCP1-dependent lipolysis. Cell Metab 2013 Jul 2;18(1):118-29. PMID: 23823482
