DataSet Record GDS3809: Expression Profiles Data Analysis Tools Sample Subsets
Title: TNF receptor and lymphotoxin beta -receptor activation effect on aortic smooth muscle cells in vitro: time course
Cluster AnalysisGDS3809 Cluster Image
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Summary: Analysis of cultured aortic smooth muscle cells (SMCs) stimulated with a combination of tumor necrosis factor (TNF) and α-LTβR monoclonal antibody for up to 24 hours. SMCs stimulated by TNF/α-LTβR mAb, but not with either agent alone, differentiate into lymphoid tissue organizer (LTO)-like cells
Organism: Mus musculus
Platform: GPL1261: [Mouse430_2] Affymetrix Mouse Genome 430 2.0 Array
Citations:
  • Lötzer K, Döpping S, Connert S, Gräbner R et al. Mouse aorta smooth muscle cells differentiate into lymphoid tissue organizer-like cells on combined tumor necrosis factor receptor-1/lymphotoxin beta-receptor NF-kappaB signaling. Arterioscler Thromb Vasc Biol 2010 Mar;30(3):395-402. PMID: 20139367
  • Gerdes N. From bystander to commander: how smooth muscle cells promote lymphoid tissue neogenesis. Arterioscler Thromb Vasc Biol 2010 Mar;30(3):393-4. PMID: 20139359
Reference Series: GSE15062 Sample count: 21
Value type: count Series published: 2009/11/23