DataSet Record GDS3885: Expression Profiles Data Analysis Tools Sample Subsets
Title: Glioblastoma stem-like cell lines, glioblastomas, and glioma cell lines
Cluster AnalysisGDS3885 Cluster Image
Summary: Analysis of glioblastoma stem-like (GS) cell lines, corresponding glioblastoma primary tumors, conventional glioma cell lines, and GS neurospheres. Results provide insight into cell lines recapitulating transcriptional aspects of glioblastomas, thereby allowing identification of therapeutic targets.
Organism: Homo sapiens
Platform: GPL570: [HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array
  • Schulte A, Günther HS, Phillips HS, Kemming D et al. A distinct subset of glioma cell lines with stem cell-like properties reflects the transcriptional phenotype of glioblastomas and overexpresses CXCR4 as therapeutic target. Glia 2011 Apr;59(4):590-602. PMID: 21294158
  • Günther HS, Schmidt NO, Phillips HS, Kemming D et al. Glioblastoma-derived stem cell-enriched cultures form distinct subgroups according to molecular and phenotypic criteria. Oncogene 2008 May 1;27(20):2897-909. PMID: 18037961
  • Zamykal M, Martens T, Matschke J, Günther HS et al. Inhibition of intracerebral glioblastoma growth by targeting the insulin-like growth factor 1 receptor involves different context-dependent mechanisms. Neuro Oncol 2015 Aug;17(8):1076-85. PMID: 25543125
Reference Series: GSE23806 Sample count: 92
Value type: transformed count Series published: 2011/02/12