DataSet Record GDS4065: Expression Profiles Data Analysis Tools Sample Subsets
Title: Effect of estrogen receptor- or retinoic acid receptor-knockdown on estrogen-sensitive MCF7 breast cancer cells
Cluster AnalysisGDS4065 Cluster Image
Summary: Analysis of MCF7 cells transfected with control siRNA, estrogen receptor α (ER) siRNA or retinoic acid receptor α (RARα) siRNA. Basal proliferation of MCF7 cells was diminished by knocking down ER or RARα. Results provided insight into the molecular basis of basal proliferation.
Organism: Homo sapiens
Platform: GPL570: [HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array
  • Salazar MD, Ratnam M, Patki M, Kisovic I et al. During hormone depletion or tamoxifen treatment of breast cancer cells the estrogen receptor apoprotein supports cell cycling through the retinoic acid receptor α1 apoprotein. Breast Cancer Res 2011 Feb 7;13(1):R18. PMID: 21299862
Reference Series: GSE26298 Sample count: 12
Value type: count Series published: 2011/05/13