Effect of full-term pregnancy or hormone treatment on inguinal left mammary gland
Summary:
Analysis of mammary gland of metestrus Lewis females randomly assigned to 3 groups: control, pregnancy, or hormone (exogenous estrogen and progesterone). Full-term pregnancy or treatment with hormone reduces breast cancer risk. Results provide insight into molecular basis of the protective effect.
GPL1355:
[Rat230_2] Affymetrix Rat Genome 230 2.0 Array
Citation:
Misra Y, Bentley PA, Bond JP, Tighe S et al. Mammary gland morphological and gene expression changes underlying pregnancy protection of breast cancer tumorigenesis. Physiol Genomics 2012 Jan 18;44(1):76-88. PMID: 22085904
