DataSet Record GDS4120: Expression Profiles Data Analysis Tools Sample Subsets
Title: Androgen deprivation effect on prostate xenograft tumor LuCaP35
Cluster AnalysisGDS4120 Cluster Image
Summary: NOD/SCID mice with established LuCaP35 xenografts were castrated, and tumors were isolated 4 weeks later. Androgen deprivation regresses androgen-dependent disease, but relapse often occurs in an androgen-independent manner. Results provide insight into the molecular basis of castration resistance.
Organism: Homo sapiens
Platform: GPL570: [HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array
  • Sun Y, Wang BE, Leong KG, Yue P et al. Androgen deprivation causes epithelial-mesenchymal transition in the prostate: implications for androgen-deprivation therapy. Cancer Res 2012 Jan 15;72(2):527-36. PMID: 22108827
Reference Series: GSE33316 Sample count: 10
Value type: count Series published: 2011/12/06