DataSet Record GDS4125: Expression Profiles Data Analysis Tools Sample Subsets
Title: Pten-null, K-ras-activated prostate cancer model
Cluster AnalysisGDS4125 Cluster Image
Summary: Analysis of prostate tumors from mutants with prostate-specific Pten loss and K-ras activation. In murine models, PTEN deletion alone fails to mimic end stage of human prostate cancer (PC). Results provide insight into cooperation between PTEN loss and RAS activation to promote EMT and metastasis.
Organism: Mus musculus
Platform: GPL1261: [Mouse430_2] Affymetrix Mouse Genome 430 2.0 Array
  • Mulholland DJ, Kobayashi N, Ruscetti M, Zhi A et al. Pten loss and RAS/MAPK activation cooperate to promote EMT and metastasis initiated from prostate cancer stem/progenitor cells. Cancer Res 2012 Apr 1;72(7):1878-89. PMID: 22350410
Reference Series: GSE34839 Sample count: 6
Value type: transformed count Series published: 2012/02/28