Analysis of lymphoid cell lines of Hodgkin, non-Hodgkin, and acute leukemia origin. Aberrant NOTCH activity is involved in the pathogenesis of B cell-derived lymphomas. Results provide insight into the molecular basis of deregulated NOTCH activity.
GPL570:
[HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array
Citation:
Köchert K, Ullrich K, Kreher S, Aster JC et al. High-level expression of Mastermind-like 2 contributes to aberrant activation of the NOTCH signaling pathway in human lymphomas. Oncogene 2011 Apr 14;30(15):1831-40. PMID: 21119597