DataSet Record GDS4181: Expression Profiles Data Analysis Tools Sample Subsets
Title: WHO 2008-classified acute myeloid leukemia subgroups (Analysis I): bone marrow mononuclear cells
Cluster AnalysisGDS4181 Cluster Image
Summary: Analysis of BMMCs from untreated patients diagnosed as AML-MLD-sole (AML with myelodysplasia-related changes solely because of multilineage dysplasia) or AML-NOS (AML-not otherwise specified) according to WHO 2008 guidelines. Results provide insight into the relevance of MLD for AML classification.
Organism: Homo sapiens
Platform: GPL570: [HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array
  • Miesner M, Haferlach C, Bacher U, Weiss T et al. Multilineage dysplasia (MLD) in acute myeloid leukemia (AML) correlates with MDS-related cytogenetic abnormalities and a prior history of MDS or MDS/MPN but has no independent prognostic relevance: a comparison of 408 cases classified as "AML not otherwise specified" (AML-NOS) or "AML with myelodysplasia-related changes" (AML-MRC). Blood 2010 Oct 14;116(15):2742-51. PMID: 20581309
Reference Series: GSE21261 Sample count: 80
Value type: transformed count Series published: 2011/01/01