DataSet Record GDS4185: Expression Profiles Data Analysis Tools Sample Subsets
Title: Systemic Lupus Erythematosus: mononuclear cells
Cluster AnalysisGDS4185 Cluster Image
Download
Summary: Analysis of freshly isolated lymphocyte (CD4+ T cells and CD19+ B cells) and CD33+ myeloid subsets from the blood of Systemic Lupus Erythematosus (SLE) patients. Results provide insight into the molecular mechanisms underlying SLE pathogenesis.
Organism: Homo sapiens
Platform: GPL96: [HG-U133A] Affymetrix Human Genome U133A Array
Citations:
  • Hutcheson J, Scatizzi JC, Siddiqui AM, Haines GK 3rd et al. Combined deficiency of proapoptotic regulators Bim and Fas results in the early onset of systemic autoimmunity. Immunity 2008 Feb;28(2):206-17. PMID: 18275831
  • Becker AM, Dao KH, Han BK, Kornu R et al. SLE peripheral blood B cell, T cell and myeloid cell transcriptomes display unique profiles and each subset contributes to the interferon signature. PLoS One 2013;8(6):e67003. PMID: 23826184
Reference Series: GSE10325 Sample count: 67
Value type: count Series published: 2008/03/01