Polycomb repressive complex 1 protein Bmi1 transduced CCE embryonic stem cells and differentiated embryoid body samples
Summary:
Analysis of Bmi1 transduced CCE embryonic stem cells (ESC) and CCE ESC differentiated by embryoid body assay. Bmi1 is essential for maintaining the pool of adult stem cells. Results provide insight into role of Bmi1 in ESC-derived hematopoietic cell transition from pluripotency to differentiation.
Ding X, Lin Q, Ensenat-Waser R, Rose-John S et al. Polycomb group protein Bmi1 promotes hematopoietic cell development from embryonic stem cells. Stem Cells Dev 2012 Jan;21(1):121-32. PMID: 21545235