Protein kinase HIPK2 overexpression effect on Human Embryonic Kidney cells
Summary:
Analysis of HEK293 cells transfected with homeo-domain interacting protein kinase 2 (HIPK2) and HIPK2-DN mutant. HIPK2 mediates renal fibrosis in 3 mouse models of renal fibrosis (Tg26, UUO, folic-acidinduced renal fibrosis). Results provide further insight into role of HIPK2 in kidney fibrosis.
GPL6244:
[HuGene-1_0-st] Affymetrix Human Gene 1.0 ST Array [transcript (gene) version]
Citation:
Jin Y, Ratnam K, Chuang PY, Fan Y et al. A systems approach identifies HIPK2 as a key regulator of kidney fibrosis. Nat Med 2012 Mar 11;18(4):580-8. PMID: 22406746
