DataSet Record GDS4235: Expression Profiles Data Analysis Tools Sample Subsets
Title: Programmed Death 1 antibody effect on pathogenic Simian Immunodeficiency Virus infection: peripheral blood mononuclear cells
Cluster AnalysisGDS4235 Cluster Image
Summary: Analysis of PBMCs from SIVmac251-infected (12 wks) rhesus macaques (RMs) treated with an antibody against Programmed Death-1 (PD-1) for 14 days. Results provide insight into the molecular mechanisms by which PD-1 blockade enhances survival of SIV-infected RMs.
Organism: Macaca mulatta
Platform: GPL3535: [Rhesus] Affymetrix Rhesus Macaque Genome Array
  • Dyavar Shetty R, Velu V, Titanji K, Bosinger SE et al. PD-1 blockade during chronic SIV infection reduces hyperimmune activation and microbial translocation in rhesus macaques. J Clin Invest 2012 May;122(5):1712-6. PMID: 22523065
Reference Series: GSE33933 Sample count: 10
Value type: transformed count Series published: 2012/04/27