DataSet Record GDS4236: Expression Profiles Data Analysis Tools Sample Subsets
Title: Rapamycin-resistant diffuse large B-cell lymphoma cell lines
Cluster AnalysisGDS4236 Cluster Image
Summary: Analysis of diffuse large B-cell lymphoma (DLBCL) cell lines resistant to rapamycin, the prototypical mTOR (mammalian Target Of Rapamycin) inhibitor. The mTOR pathway is constitutively activated in DLBCL. Results provide insight into mechanisms of resistance to mTOR inhibition in DLBCL.
Organism: Homo sapiens
Platform: GPL6244: [HuGene-1_0-st] Affymetrix Human Gene 1.0 ST Array [transcript (gene) version]
  • Petrich AM, Leshchenko V, Kuo PY, Xia B et al. Akt inhibitors MK-2206 and nelfinavir overcome mTOR inhibitor resistance in diffuse large B-cell lymphoma. Clin Cancer Res 2012 May 1;18(9):2534-44. PMID: 22338016
Reference Series: GSE27255 Sample count: 14
Value type: transformed count Series published: 2012/04/30