Oxidized low-density lipoprotein effect on LOX-1 overexpressing aortic endothelial cell line HAECT: time course
Summary:
Analysis of oxidized-low-density lipoprotein receptor-1 (LOX-1)-overexpressing HAECT cells treated with OxLDL for up to 24 hrs. OxLDL is implicated as a proatherogenic factor. Results provide insight into molecular mechanisms underlying OxLDL-induced endothelial dysfunction and atherosclerosis.
GPL570:
[HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array
Citation:
Mattaliano MD, Huard C, Cao W, Hill AA et al. LOX-1-dependent transcriptional regulation in response to oxidized LDL treatment of human aortic endothelial cells. Am J Physiol Cell Physiol 2009 Jun;296(6):C1329-37. PMID: 19279231
