DataSet Record GDS4274: Expression Profiles Data Analysis Tools Sample Subsets
Title: Stratification of pediatric septic shock patients: whole blood
Cluster AnalysisGDS4274 Cluster Image
Summary: Analysis of whole blood from children (up to 10 years old) within 24hrs of PICU admission for septic shock. Heterogeneous clinical phenotypes stratify the septic shock patients. Results provide insight into the molecular mechanisms underlying these septic shock subgroups.
Organism: Homo sapiens
Platform: GPL570: [HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array
  • Wong HR, Cvijanovich N, Lin R, Allen GL et al. Identification of pediatric septic shock subclasses based on genome-wide expression profiling. BMC Med 2009 Jul 22;7:34. PMID: 19624809
  • Wynn JL, Cvijanovich NZ, Allen GL, Thomas NJ et al. The influence of developmental age on the early transcriptomic response of children with septic shock. Mol Med 2011;17(11-12):1146-56. PMID: 21738952
  • Grunwell JR, Weiss SL, Cvijanovich NZ, Allen GL et al. Differential expression of the Nrf2-linked genes in pediatric septic shock. Crit Care 2015 Sep 17;19:327. PMID: 26376786
  • Wong HR, Cvijanovich NZ, Allen GL, Thomas NJ et al. Corticosteroids are associated with repression of adaptive immunity gene programs in pediatric septic shock. Am J Respir Crit Care Med 2014 Apr 15;189(8):940-6. PMID: 24650276
Reference Series: GSE26440 Sample count: 130
Value type: transformed count Series published: 2011/01/13