Mixed lineage leukemia gene rearrangements in acute myeloid leukemia: bone marrow mononuclear cells
Summary:
Analysis of bone marrow cells from AML cases representing MLL chromosomal translocation (tMLL) or partial tandem duplication (MLL-PTD). Rearrangements of MLL at chromosome 11q23 are commonly involved in acute leukemia. Results provide insight into molecular heterogeneity between MLL-PTD and tMLL.
GPL570:
[HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array
Citation:
Liu HC, Shih LY, May Chen MJ, Wang CC et al. Expression of HOXB genes is significantly different in acute myeloid leukemia with a partial tandem duplication of MLL vs. a MLL translocation: a cross-laboratory study. Cancer Genet 2011 May;204(5):252-9. PMID: 21665178
