Interleukin 1β effect on insulinoma cell line overexpressing pancreatic duodenum homeobox 1: time course
Summary:
Analysis of pancreatic duodenum homeobox 1 (Pdx1)-overexpressing, INS-1ab insulinoma cell line exposed to Interleukin 1b (IL-1β) cytokine for up to 24 hrs. Results provide insight into the molecular mechanisms underlying Pdx1-driven potentiation of beta cell sensitivity to IL-1β.
GPL1355:
[Rat230_2] Affymetrix Rat Genome 230 2.0 Array
Citation:
Hansen JB, Tonnesen MF, Madsen AN, Hagedorn PH et al. Divalent metal transporter 1 regulates iron-mediated ROS and pancreatic β cell fate in response to cytokines. Cell Metab 2012 Oct 3;16(4):449-61. PMID: 23000401
