DataSet Record GDS4343: Expression Profiles Data Analysis Tools Sample Subsets
Title: Xenograft tumors generated from iKras p53 null pancreatic ductal adenocarcinoma cell lines
Cluster AnalysisGDS4343 Cluster Image
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Summary: Analysis of xenograft tumors generated from independent iKras p53L/+ PDAC cell lines. Cultured parental lines also examined. Doxycycline treatment induced expression of oncogenic KrasG12D. Results provide insight into the molecular mechanisms underlying KrasG12D-mediated PDAC tumor maintenance.
Organism: Mus musculus
Platform: GPL1261: [Mouse430_2] Affymetrix Mouse Genome 430 2.0 Array
Citation:
  • Ying H, Kimmelman AC, Lyssiotis CA, Hua S et al. Oncogenic Kras maintains pancreatic tumors through regulation of anabolic glucose metabolism. Cell 2012 Apr 27;149(3):656-70. PMID: 22541435
Reference Series: GSE32277 Sample count: 33
Value type: count Series published: 2012/04/30