Normal colonic lamina propria macrophage and dendritic cell populations
Summary:
Analysis of sorted, steady-state colonic cells subdivided into 4 populations: 2 DC subsets and 2 MP subsets based on CD11c and F4/80 expression. DCs and MPs are important for immunological homeostasis in colon. Results provide insight into molecular characterization of colonic MP and DC populations.
Rivollier A, He J, Kole A, Valatas V et al. Inflammation switches the differentiation program of Ly6Chi monocytes from antiinflammatory macrophages to inflammatory dendritic cells in the colon. J Exp Med 2012 Jan 16;209(1):139-55. PMID: 22231304