DataSet Record GDS4401: Expression Profiles Data Analysis Tools Sample Subsets
Title: H9 hESC-derived neural stem cells harboring pathogenic leucine-rich repeat kinase 2 mutation
Cluster AnalysisGDS4401 Cluster Image
Summary: Analysis of LRRK2 (Gly2019Ser) mutant neural stem cells (NSC) treated with LRRK2 kinase specific inhibitor LRRK2-IN-1. The LRRK2 (G2019S) mutation causes familial Parkinson's disease. Results provide insight into molecular basis of progressive degeneration of NSCs caused by pathogenic LRRK2.
Organism: Homo sapiens
Platform: GPL571: [HG-U133A_2] Affymetrix Human Genome U133A 2.0 Array
  • Liu GH, Qu J, Suzuki K, Nivet E et al. Progressive degeneration of human neural stem cells caused by pathogenic LRRK2. Nature 2012 Nov 22;491(7425):603-7. PMID: 23075850
Reference Series: GSE36321 Sample count: 9
Value type: count Series published: 2012/10/17