cAMP agonist forskolin effect on INS-1 insulinoma cell line: time course
Summary:
Analysis of insulinoma cells after short-term (2hr) and long-term (16hr) stimulation with cAMP agonist forskolin. Incretin hormone GLP-1 enhances islet cell survival via cAMP pathway induction in beta cells. Results provide insight into mechanisms by which GLP-1 promotes pancreatic islet viability.
GPL6247:
[RaGene-1_0-st] Affymetrix Rat Gene 1.0 ST Array [transcript (gene) version]
Citation:
Van de Velde S, Hogan MF, Montminy M. mTOR links incretin signaling to HIF induction in pancreatic beta cells. Proc Natl Acad Sci U S A 2011 Oct 11;108(41):16876-82. PMID: 21949366
