Analysis of circulating CD4+ and CD8+ T-cells from adult patients with severe or nonsevere asthma. CD4+ T cells contribute to the development and maintenance of an inflammatory response in asthmatic patients. Results provide insight into the role of CD8+ T cells in severe asthma.
GPL570:
[HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array
Citation:
Tsitsiou E, Williams AE, Moschos SA, Patel K et al. Transcriptome analysis shows activation of circulating CD8+ T cells in patients with severe asthma. J Allergy Clin Immunol 2012 Jan;129(1):95-103. PMID: 21917308
