Intraportal tacrolimus flushing effect on liver allograft
Summary:
Analysis of wedge biopsies from hepatic allografts perfused intraportally with tacrolimus before transplantation. Tacrolimus, a calcineurin inhibitor, ameliorates ischemic reperfusion injury. Results provide insight into the effect of tacrolimus on the inflammatory response of the donor graft.
GPL11209:
[HuGene10stv1_Hs_ENSG] Affymetrix GeneChip Human Gene 1.0 ST Array [Brainarray Version 12]
Citation:
Kristo I, Wilflingseder J, Kainz A, Marschalek J et al. Effect of intraportal infusion of tacrolimus on ischaemic reperfusion injury in orthotopic liver transplantation: a randomized controlled trial. Transpl Int 2011 Sep;24(9):912-9. PMID: 21672049