DataSet Record GDS4463: Expression Profiles Data Analysis Tools Sample Subsets
Title: Endothelial cells from P8 neonatal retina [MG_U74Cv2]
Cluster AnalysisGDS4463 Cluster Image
Summary: Analysis of FACS-sorted, GFP-positive endothelial cells from retinas of postnatal day 8 (P8) homozygous Tie2-GFP transgenics. Deregulated retinal angiogenesis causes vision loss in many ocular diseases. Results provide insight into the molecular mechanisms underlying intraretinal angiogenesis.
Organism: Mus musculus
Platform: GPL83: [MG_U74Cv2] Affymetrix Murine Genome U74 Version 2 Array
  • Fukushima Y, Okada M, Kataoka H, Hirashima M et al. Sema3E-PlexinD1 signaling selectively suppresses disoriented angiogenesis in ischemic retinopathy in mice. J Clin Invest 2011 May;121(5):1974-85. PMID: 21505259
  • Kusuhara S, Fukushima Y, Fukuhara S, Jakt LM et al. Arhgef15 promotes retinal angiogenesis by mediating VEGF-induced Cdc42 activation and potentiating RhoJ inactivation in endothelial cells. PLoS One 2012;7(9):e45858. PMID: 23029280
  • Ogura S, Kurata K, Hattori Y, Takase H et al. Sustained inflammation after pericyte depletion induces irreversible blood-retina barrier breakdown. JCI Insight 2017 Feb 9;2(3):e90905. PMID: 28194443
Reference Series: GSE27238 Sample count: 6
Value type: count Series published: 2011/04/17