DataSet Record GDS4472: Expression Profiles Data Analysis Tools Sample Subsets
Title: Transcription factor OTX2 oncogene silencing effect on D425 medulloblastoma cell line: time course
Cluster AnalysisGDS4472 Cluster Image
Summary: Analysis of D425 medulloblastoma (MB) cells with doxycyline inducible shRNA against OTX2, sampled 0 to 96 hrs after induction in 3 independent time courses (TC). OTX2 is implicated as an oncogene in childhood MB. Results provide insight into role of OTX2 in medulloblastoma.
Organism: Homo sapiens
Platform: GPL570: [HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array
  • Bunt J, Hasselt NE, Zwijnenburg DA, Hamdi M et al. OTX2 directly activates cell cycle genes and inhibits differentiation in medulloblastoma cells. Int J Cancer 2012 Jul 15;131(2):E21-32. PMID: 21964830
Reference Series: GSE22875 Sample count: 24
Value type: count Series published: 2012/07/04