DataSet Record GDS4488: Expression Profiles Data Analysis Tools Sample Subsets
Title: Notch1 signaling inhibition effect on aortic valve interstitial cells
Cluster AnalysisGDS4488 Cluster Image
Summary: Analysis of aortic valve interstitial cells treated with the Notch1 signaling inhibitor DAPT. NOTCH1 mutations are associated with aortic valve malformations and adult-onset calcification. Results provide insight into the role of Notch in the pathogenesis of calcific aortic valve disease.
Organism: Rattus norvegicus
Platform: GPL1355: [Rat230_2] Affymetrix Rat Genome 230 2.0 Array
  • Acharya A, Hans CP, Koenig SN, Nichols HA et al. Inhibitory role of Notch1 in calcific aortic valve disease. PLoS One 2011;6(11):e27743. PMID: 22110751
Reference Series: GSE31668 Sample count: 6
Value type: transformed count Series published: 2011/08/26