DataSet Record GDS4490: Expression Profiles Data Analysis Tools Sample Subsets
Title: Lmna G609G knock-in model of Hutchinson-Gilford Progeria Syndrome: liver
Cluster AnalysisGDS4490 Cluster Image
Summary: Analysis of liver from Lmna Gly609Gly knock-in C57BL/6 females. These mice accumulate progerin and manifest the main clinical features of human Hutchinson-Gilford progeria syndrome (HGPS). Results provide insight into the molecular mechanisms underlying HGPS.
Organism: Mus musculus
Platform: GPL6246: [MoGene-1_0-st] Affymetrix Mouse Gene 1.0 ST Array [transcript (gene) version]
  • Osorio FG, Navarro CL, Cadiñanos J, López-Mejía IC et al. Splicing-directed therapy in a new mouse model of human accelerated aging. Sci Transl Med 2011 Oct 26;3(106):106ra107. PMID: 22030750
Reference Series: GSE32609 Sample count: 6
Value type: count Series published: 2012/01/13