Melanoma models with contrasting metastatic potential
Summary:
Analysis of primary cutaneous melanomas derived from iMet (metastasis-capable) and iHRAS* (non-metastatic) models. Results provide insight into the molecular mechanisms underlying metastatic potential.
Scott KL, Nogueira C, Heffernan TP, van Doorn R et al. Proinvasion metastasis drivers in early-stage melanoma are oncogenes. Cancer Cell 2011 Jul 12;20(1):92-103. PMID: 21741599