Interleukin-10 effect on peripheral blood mononuclear cells
Summary:
Analysis of healthy PBMCs stimulated with IL-10. PBMC results integrated with tuberculosis and leprosy transcriptional profiles provide insight into molecular mechanisms by which type I interferons (e.g., IFN-β and downstream gene IL-10) may suppress type II interferon anti-mycobacterial responses.
GPL570:
[HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array
Citation:
Teles RM, Graeber TG, Krutzik SR, Montoya D et al. Type I interferon suppresses type II interferon-triggered human anti-mycobacterial responses. Science 2013 Mar 22;339(6126):1448-53. PMID: 23449998