Transactive response DNA-binding Protein (TDP-1) loss-of-function mutants
Summary:
Analysis of tdp-1(ok803lf) mutants. TDP-1 loss alleviates proteotoxicity and extends life span. Results provide insight into a role for TDP-1 in the regulation of protein homeostasis and aging.
GPL200:
[Celegans] Affymetrix C. elegans Genome Array
Citation:
Zhang T, Hwang HY, Hao H, Talbot C Jr et al. Caenorhabditis elegans RNA-processing protein TDP-1 regulates protein homeostasis and life span. J Biol Chem 2012 Mar 9;287(11):8371-82. PMID: 22232551
