DataSet Record GDS4602: Expression Profiles Data Analysis Tools Sample Subsets
Title: Psoriasis lesional and non-lesional skin
Cluster AnalysisGDS4602 Cluster Image
Summary: Analysis of skin punch biopsies from lesional skin (involved sample) and non-lesional skin (uninvolved sample) from each psoriatic patient. Psoriasis is an immune-mediated, inflammatory and hyperproliferative disease of skin and joints. Results provide insight into the molecular basis of psoriasis.
Organism: Homo sapiens
Platform: GPL570: [HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array
  • Nair RP, Duffin KC, Helms C, Ding J et al. Genome-wide scan reveals association of psoriasis with IL-23 and NF-kappaB pathways. Nat Genet 2009 Feb;41(2):199-204. PMID: 19169254
  • Swindell WR, Johnston A, Carbajal S, Han G et al. Genome-wide expression profiling of five mouse models identifies similarities and differences with human psoriasis. PLoS One 2011 Apr 4;6(4):e18266. PMID: 21483750
  • Ding J, Gudjonsson JE, Liang L, Stuart PE et al. Gene expression in skin and lymphoblastoid cells: Refined statistical method reveals extensive overlap in cis-eQTL signals. Am J Hum Genet 2010 Dec 10;87(6):779-89. PMID: 21129726
Reference Series: GSE13355 Sample count: 180
Value type: transformed count Series published: 2009/01/25