Corticosterone effect on hippocampus: dose response
Summary:
Analysis of hippocampal CA1 from adrenalectomized F344 males maintained for 3 months with implanted corticosterone (CORT) pellets to produce low or intermediate (glucocorticoid receptor-activating) blood levels of CORT. Results provide insight into the effects of chronic CORT on the hippocampus.
Chen KC, Blalock EM, Curran-Rauhut MA, Kadish I et al. Glucocorticoid-dependent hippocampal transcriptome in male rats: pathway-specific alterations with aging. Endocrinology 2013 Aug;154(8):2807-20. PMID: 23736296