DataSet Record GDS4770: Expression Profiles Data Analysis Tools Sample Subsets
Title: Cmah knockout effect on mdx model of Duchenne Muscular Dystrophy (DMD): cardiac muscle
Cluster AnalysisGDS4770 Cluster Image
Summary: Analysis of muscle from mdx males with a human-specific deletion in the Cmah (cytidine monophosphate-sialic acid hydroxylase) gene. Cmah-/-mdx mice show increased disease severity that better approximates DMD in humans. Results provide insight into the contributions of glycosylation defects to DMD.
Organism: Mus musculus
Platform: GPL1261: [Mouse430_2] Affymetrix Mouse Genome 430 2.0 Array
  • Chandrasekharan K, Yoon JH, Xu Y, deVries S et al. A human-specific deletion in mouse Cmah increases disease severity in the mdx model of Duchenne muscular dystrophy. Sci Transl Med 2010 Jul 28;2(42):42ra54. PMID: 20668298
Reference Series: GSE16438 Sample count: 12
Value type: count Series published: 2010/07/31