MEKK2 and MEKK3 deficiency effect on CD26L(low)CD44(high) CD4 T cells
Summary:
Analysis of CD26L(low)CD44(high) CD4(+) T cells deficient for MEKK2 and MEKK3, conserved members of the MEK kinase (MEKK) subgroup of the MAP3K superfamily. Results provide insight into the role of MEKK2 and MEKK3 in helper T cell differentiation.
Chang X, Liu F, Wang X, Lin A et al. The kinases MEKK2 and MEKK3 regulate transforming growth factor-β-mediated helper T cell differentiation. Immunity 2011 Feb 25;34(2):201-12. PMID: 21333552
