n-3 polyunsaturated fatty acid depletion effect on the liver
Summary:
Analysis of livers from C57Bl/6J males fed an n-3 polyunsaturated fatty acid (n-3 PUFA) depleted diet for 3 months. Livers examined at the fed and fasting state. Result provide insight into the molecular mechanisms underlying the development of hepatic steatosis associated with n-3 PUFA depletion.
Pachikian BD, Essaghir A, Demoulin JB, Neyrinck AM et al. Hepatic n-3 polyunsaturated fatty acid depletion promotes steatosis and insulin resistance in mice: genomic analysis of cellular targets. PLoS One 2011;6(8):e23365. PMID: 21853118
