MCF10A mammary epithelial cell line transfected with miR-221/222 mimic
Summary:
Analysis MCF10A cells transfected with synthetic oligo mimics for microRNAs (miRNAs) miR-221 and miR-222. Both miRNAs are abundant in the basal-like subtype of breast cancer but not in the luminal subtype. Results provide insight in to the role of miR-221/222 in the pathogenesis of breast cancer.
GPL570:
[HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array
Citation:
Stinson S, Lackner MR, Adai AT, Yu N et al. TRPS1 targeting by miR-221/222 promotes the epithelial-to-mesenchymal transition in breast cancer. Sci Signal 2011 Jun 14;4(177):ra41. PMID: 21673316