DataSet Record GDS4801: Expression Profiles Data Analysis Tools Sample Subsets
Title: Neural transcription factor SOX11 depletion effect on mantle cell lymphoma cell line
Cluster AnalysisGDS4801 Cluster Image
Summary: Analysis of Z138 mantle cell lymphoma (MCL) cells depleted for the neural transcription factor SOX11. SOX11 is overexpressed in aggressive lymphoid neoplasms mainly in MCL. Results provide insight into the role of SOX11 in the pathogenesis of MCL.
Organism: Homo sapiens
Platform: GPL570: [HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array
  • Vegliante MC, Palomero J, Pérez-Galán P, Roué G et al. SOX11 regulates PAX5 expression and blocks terminal B-cell differentiation in aggressive mantle cell lymphoma. Blood 2013 Mar 21;121(12):2175-85. PMID: 23321250
  • Palomero J, Vegliante MC, Rodríguez ML, Eguileor A et al. SOX11 promotes tumor angiogenesis through transcriptional regulation of PDGFA in mantle cell lymphoma. Blood 2014 Oct 2;124(14):2235-47. PMID: 25092176
Reference Series: GSE34763 Sample count: 4
Value type: count Series published: 2013/04/04