DataSet Record GDS4814: Expression Profiles Data Analysis Tools Sample Subsets
Title: Ovarian cancer xenograft tumor response to trastuzumab and pertuzumab
Cluster AnalysisGDS4814 Cluster Image
Summary: Analysis of SKOV3 ovarian cancer xenograft tumors treated with trastuzumab (TZ), pertuzumab (PZ), or both. TZ and PZ target Human Epidermal Growth Factor Receptor 2 (HER2). Combined therapy results in enhanced antitumor activity. Results provide insight into the molecular basis of this enhancement.
Organism: Homo sapiens
Platform: GPL6947: Illumina HumanHT-12 V3.0 expression beadchip
  • Sims AH, Zweemer AJ, Nagumo Y, Faratian D et al. Defining the molecular response to trastuzumab, pertuzumab and combination therapy in ovarian cancer. Br J Cancer 2012 May 22;106(11):1779-89. PMID: 22549178
Reference Series: GSE31432 Sample count: 23
Value type: count Series published: 2012/05/03