DataSet Record GDS4823: Expression Profiles Data Analysis Tools Sample Subsets
Title: SIRT4 deficiency effect on the liver
Cluster AnalysisGDS4823 Cluster Image
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Summary: Analysis of livers from sirtuin 4 (SIRT4)-null, 129SV males. Fatty acid oxidation rates are higher in SIRT4 knockout hepatocytes than in wildtype cells. Results provide insight into the role of SIRT4 in hepatic lipid metabolism.
Organism: Mus musculus
Platform: GPL1261: [Mouse430_2] Affymetrix Mouse Genome 430 2.0 Array
Citation:
  • Laurent G, de Boer VC, Finley LW, Sweeney M et al. SIRT4 represses peroxisome proliferator-activated receptor α activity to suppress hepatic fat oxidation. Mol Cell Biol 2013 Nov;33(22):4552-61. PMID: 24043310
Reference Series: GSE56321 Sample count: 12
Value type: count Series published: 2014/03/28