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DataSet Record GDS4823:
Expression Profiles
Data Analysis Tools
Sample Subsets
Title:
SIRT4 deficiency effect on the liver
Cluster Analysis
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Summary:
Analysis of livers from sirtuin 4 (SIRT4)-null, 129SV males. Fatty acid oxidation rates are higher in SIRT4 knockout hepatocytes than in wildtype cells. Results provide insight into the role of SIRT4 in hepatic lipid metabolism.
Organism:
Mus musculus
Platform:
GPL1261
: [Mouse430_2] Affymetrix Mouse Genome 430 2.0 Array
Citation:
Laurent G, de Boer VC, Finley LW, Sweeney M et al.
SIRT4 represses peroxisome proliferator-activated receptor α activity to suppress hepatic fat oxidation.
Mol Cell Biol
2013 Nov;33(22):4552-61. PMID:
24043310
Reference Series:
GSE56321
Sample count:
12
Value type:
count
Series published:
2014/03/28