Human polyomavirus JC virus (JCV) infection of clonal immortalized glial SVG cells
Summary:
Analysis of fetal glial cell line SVG-derived clones 10B1 and 5F4 following infection with JCV. Clone SVG-5F4 shows low levels of viral growth, whereas clone SVG-10B1 is highly permissive to JCV infection. Results provide insight into cell type differences in JCV host range and pathogenesis.
GPL6244:
[HuGene-1_0-st] Affymetrix Human Gene 1.0 ST Array [transcript (gene) version]
Citation:
Ferenczy MW, Johnson KR, Steinberg SM, Marshall LJ et al. Clonal immortalized human glial cell lines support varying levels of JC virus infection due to differences in cellular gene expression. J Neuroimmune Pharmacol 2013 Dec;8(5):1303-19. PMID: 24052414
