Transcription factor Yin Yang 1 deficiency effect on the skeletal muscle
Summary:
Analysis of the soleus muscles of transcription factor Yin Yang 1 (YY1) deficient animals. Many nuclear genes encoding mitochondrial proteins contain binding sites for YY1 in their proximal promoters. Results provide insight into the role of YY1 in mitochondrial function.
Blättler SM, Verdeguer F, Liesa M, Cunningham JT et al. Defective mitochondrial morphology and bioenergetic function in mice lacking the transcription factor Yin Yang 1 in skeletal muscle. Mol Cell Biol 2012 Aug;32(16):3333-46. PMID: 22711985
