DataSet Record GDS4865: Expression Profiles Data Analysis Tools Sample Subsets
Title: P81S von Hippel-Lindau mutation effect on embryonic stem cell teratomas
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Summary: Analysis of teratomas from nude mice injected with von Hippel-Lindau (VHL)-deficient mouse ES cells stably expressing human P81S VHL protein. P81S teratomas are resistant to ionizing radiation-induced apoptosis. Results provide insight into molecular mechanisms underlying this adaptive response.
Organism: Mus musculus
Platform: GPL11533: [MoGene-1_1-st] Affymetrix Mouse Gene 1.1 ST Array [transcript (gene) version]
Citation:
  • Desimone MC, Rathmell WK, Threadgill DW. Pleiotropic effects of the trichloroethylene-associated P81S VHL mutation on metabolism, apoptosis, and ATM-mediated DNA damage response. J Natl Cancer Inst 2013 Sep 18;105(18):1355-64. PMID: 23990666
Reference Series: GSE37464 Sample count: 10
Value type: transformed count Series published: 2013/09/01