Hepatoma cell line overexpressing human Sar1 components of the coat protein complex II transport machinery
Summary:
Analysis of McArdle-RH7777 hepatoma cell lines overexpressing human SAR1A, SAR1B, or a constitutively active mutant SAR1B that cannot hydrolyze GTP to support coat protein complex II (COPII) vesicle assembly. Results provide insight into roles of the SAR1 isoforms in the COPII transport machinery.
GPL1355:
[Rat230_2] Affymetrix Rat Genome 230 2.0 Array
Citation:
Fryer LG, Jones B, Duncan EJ, Hutchison CE et al. The endoplasmic reticulum coat protein II transport machinery coordinates cellular lipid secretion and cholesterol biosynthesis. J Biol Chem 2014 Feb 14;289(7):4244-61. PMID: 24338480
